Survival in a cohort of patients with gastric adenocarcinoma undergoing gastrectomy and lymphadenectomy in a surgical reference institute, Bogota 2013-2018

Introducción. El cáncer gástrico (CG) es una patología frecuente a nivel mundial y Colombia se sitúa dentro de los países con mayor incidencia. Constituye la tercera causa de muerte por cáncer representando un problema de salud pública globalmente. El adenocarcinoma representa más del 90% de todos los tumores gástricos, su pronóstico está relacionado en gran medida con el tipo histológico y la clasificación TNM inicial, así como de la opción quirúrgica que garantice márgenes negativos y una disección de 20 o más ganglios. Métodos. Estudio observacional, de cohorte retrospectiva de pacientes con cáncer gástrico llevados a gastrectomía linfadectomia durante el periodo descrito, con un seguimiento de 2 años. Resultados. Curva de Kaplan-Meier para sobrevida global en pacientes con adenocarcinoma gástrico siendo a los 10 meses del 91.5%, a los 20 meses del 87.2%, a los 30 meses del 84.5% y a los 40 meses del 80.9%. Se encontraron diferencias significativas en la sobrevida global de los pacientes al analizarlos a partir del recibir o no adyuvancia (p=0.000), pero no se encontraron diferencias al analizar la sobrevida con variables de interés como ganglios disecados en el grupo de veinte ganglios o menos versus más de veinte ganglios (p=0,06) o el estadiaje clínico (p=0,52) Conclusión. No se encontraron diferencias significativas en la sobrevida al comparar los pacientes según el número de ganglios disecados o tipo de linfadenectomía realizada, sin embargo, se encontraron diferencias significativas en la sobrevida global de los pacientes que recibieron adyuvancia.Background. Gastric cancer is still a frequent cancer worldwide. Colombia is one of the countries with major incidence. It is the third leading cause of cancer death, and it still represents a health issue globally. Adenocarcinoma represents more than 90% of all gastric tumors and its prognose is related to the stage by the time it's diagnosed; in most cases it is an advanced stage and patient survival depends mainly on histologic type and initial TNM classification, as well as in the surgical option that guarantees negativity of margins and a lymph node resection count greater than 15. Methods. Observational descriptive retrospective study of patients diagnosed with gastric adenocarcinoma who underwent gastrectomy during the described period, with a follow-up from 2 to 5 years. Results. The Kaplan-Meier curve for overall survival in gastric adenocarcinoma was performed with 91.5% at 10 months, 87.2% at 20 months, 84.5% at 30 months and 80.9% at 40 months. Significant differences were found in the overall survival of patients when analyzing them from receipt or no adjuvancy (p=0.000), but no differences were found when analyzing the survival with variables of Interests such as dissected lymph nodes in the group of twenty lymph nodes or less versus more than twenty lymph nodes (p=0.06) or the clinical stage (p=0.52). Conclusions. No significant differences were found in survival when comparing the patients according to the number of dissected lymph nodes or the type of lymphadenectomy performed, however, significant differences were found in the overall survival of patients who received surgical management and adjuvancy