Cataloged from PDF version of thesis.Includes bibliographical reference (leaves 53-60).Thesis (M.S.): Bilkent University, Department of Molecular Biology and Genetics, İhsan Doğramacı Bilkent University, 2014.The proper functioning and the development of the cell is essential to the fitness of the multicellular organisms - any significant disturbances in cellular mechanisms can lead to a multitude of diseases or death. Among these conditions, the global rise in metabolic diseases like obesity, diabetes and atherosclerosis draw significant research interest focus. Since the prevalence of metabolic disorders in the developed and underdeveloped world is expected to increase further in next decade; understanding the contributing cellular m...
The unfolded protein response is the mechanism by which cells control endoplasmic reticulum (ER) pro...
Protein folding homeostasis in the lumen of the endoplasmic reticulum is defended by signal transduc...
Metaflammation, an atypical, metabolically induced, chronic lowgrade inflammation, plays an importan...
Ankara : The Department of Molecular Biology and Genetics and the Graduate School of Engineering and...
peer reviewedThe endoplasmic reticulum (ER) is the site of protein folding and secretion, Ca(2+) sto...
Objective: Increased fatty acids in the circulation and their accumulation in non-adipose tissues pl...
Background: The Unfolded Protein Response (UPR) is a well conserved mechanism that mammalian cells u...
The accumulation of unfolded protein in the endoplasmic reticulum (ER) causes ER stress. Cells acti...
Unfolded stress response (UPR) is a conserved cellular pathway involved in protein quality control t...
Unfolded stress response (UPR) is a conserved cellular pathway involved in protein quality control t...
Diabetes is an epidemic of worldwide proportions caused by β -cell failure. Nutrient fluctuations a...
The endoplasmic reticulum (ER) is the organelle responsible for synthesis and folding of secreted an...
The role of the endoplasmic reticulum (ER) has evolved from protein synthesis, processing, and other...
The discovery of endogenous microRNAs (miRNAs) in the early 1990s has been followed by the identific...
Diabetes mellitus comprises a cohort of genetic and metabolic diseases which are characterized by th...
The unfolded protein response is the mechanism by which cells control endoplasmic reticulum (ER) pro...
Protein folding homeostasis in the lumen of the endoplasmic reticulum is defended by signal transduc...
Metaflammation, an atypical, metabolically induced, chronic lowgrade inflammation, plays an importan...
Ankara : The Department of Molecular Biology and Genetics and the Graduate School of Engineering and...
peer reviewedThe endoplasmic reticulum (ER) is the site of protein folding and secretion, Ca(2+) sto...
Objective: Increased fatty acids in the circulation and their accumulation in non-adipose tissues pl...
Background: The Unfolded Protein Response (UPR) is a well conserved mechanism that mammalian cells u...
The accumulation of unfolded protein in the endoplasmic reticulum (ER) causes ER stress. Cells acti...
Unfolded stress response (UPR) is a conserved cellular pathway involved in protein quality control t...
Unfolded stress response (UPR) is a conserved cellular pathway involved in protein quality control t...
Diabetes is an epidemic of worldwide proportions caused by β -cell failure. Nutrient fluctuations a...
The endoplasmic reticulum (ER) is the organelle responsible for synthesis and folding of secreted an...
The role of the endoplasmic reticulum (ER) has evolved from protein synthesis, processing, and other...
The discovery of endogenous microRNAs (miRNAs) in the early 1990s has been followed by the identific...
Diabetes mellitus comprises a cohort of genetic and metabolic diseases which are characterized by th...
The unfolded protein response is the mechanism by which cells control endoplasmic reticulum (ER) pro...
Protein folding homeostasis in the lumen of the endoplasmic reticulum is defended by signal transduc...
Metaflammation, an atypical, metabolically induced, chronic lowgrade inflammation, plays an importan...