Air-guided photonic-crystal-fiber pulse-compression delivery of multimegawatt femtosecond laser output for nonlinear-optical imaging and neurosurgery
- Lanin, A.A.
- Fedotov I.V.
- Sidorov-Biryukov, D.A.
- Doronina-Amitonova L.V.
- Ivashkina O.I.
- Zots, M.A.
- Sun, C.-K.
- Ömer Ilday F.
- Fedotov, A.B.
- Anokhin, K.V.
- Zheltikov, A.M.
DOIAbstract
Large-core hollow photonic-crystal fibers (PCFs) are shown to enable a fiber-format air-guided delivery of ultrashort infrared laser pulses for neurosurgery and nonlinear-optical imaging. With an appropriate dispersion precompensation, an anomalously dispersive 15-m-core hollow PCF compresses 510-fs, 1070-nm light pulses to a pulse width of about 110 fs, providing a peak power in excess of 5 MW. The compressed PCF output is employed to induce a local photodisruption of corpus callosum tissues in mouse brain and is used to generate the third harmonic in brain tissues, which is captured by the PCF and delivered to a detector through the PCF cladding. © 2012 American Institute of Physics
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