A-Brain: Using the Cloud to Understand the Impact of Genetic Variability on the Brain

International audienceJoint genetic and neuroimaging data analysis on large cohorts of subjects is a new approach used to assess and understand the variability that exists between individuals. This approach has remained poorly understood so far and brings forward very significant challenges, as progress in this field can open pioneering directions in biology and medicine. As both neuroimaging- and genetic-domain observations represent a huge amount of variables (of the order of 106 ), performing statistically rigorous analyses on such Big Data represents a computational challenge that cannot be addressed with conventional computational techniques. In the A-Brain project, we address this computational problem using cloud computing techniques on Microsoft Azure, relying on our complementary expertise in the area of scalable cloud data management and in the field of neuroimaging and genetics data analysis