International audienceAn enantioselective synthesis of a C ring of taxol has been accomplished. The key step is an oxidative cleavage of a derivative of the Wieland-Miescher ketone. A first attempt of a Shapiro reaction modelling the coupling of the C ring with the A fragment of taxol was also successful. © 2011 Institute of Organic Chemistry and Biochemistry
2003 Spring.Includes bibliographical references.The exploration of several strategies for the synthe...
Taxol®, isolated from the bark of the Pacific yew tree (Taxus brevifolia Nutt.), is a very effective...
A highly functionalized intermediate in the synthesis of Taxol has been synthesized, which features ...
International audienceAn enantioselective synthesis of a C ring of taxol has been accomplished. The ...
A synthetic route developed for the preparation of the A-ring of Taxol family of molecules is report...
International audienceAn efficient enantioselective synthesis of the ABC tricyclic core of the antic...
An efficient enantioselective synthesis of the ABC tricyclic core of the anticancer drug Taxol is re...
The topic of this thesis is the synthesis of Taxane derivatives using the asymmetric conjugate addit...
International audienceHydrazone 30, precursor of a taxoid C-ring, was synthesized in 7 steps from co...
Taxol is one of the world’s most successful drugs used in the treatment of cancers. Isolated from t...
The crucial highly functionalized CD substructure of taxol has been synthesized featuring a stereoco...
Taxol is a natural compound discovered in 1965 from an extract of yew tree (Taxus Brevifolia Nutt.)....
2003 Spring.Includes bibliographical references.The exploration of several strategies for the synthe...
Taxol®, isolated from the bark of the Pacific yew tree (Taxus brevifolia Nutt.), is a very effective...
A highly functionalized intermediate in the synthesis of Taxol has been synthesized, which features ...
International audienceAn enantioselective synthesis of a C ring of taxol has been accomplished. The ...
A synthetic route developed for the preparation of the A-ring of Taxol family of molecules is report...
International audienceAn efficient enantioselective synthesis of the ABC tricyclic core of the antic...
An efficient enantioselective synthesis of the ABC tricyclic core of the anticancer drug Taxol is re...
The topic of this thesis is the synthesis of Taxane derivatives using the asymmetric conjugate addit...
International audienceHydrazone 30, precursor of a taxoid C-ring, was synthesized in 7 steps from co...
Taxol is one of the world’s most successful drugs used in the treatment of cancers. Isolated from t...
The crucial highly functionalized CD substructure of taxol has been synthesized featuring a stereoco...
Taxol is a natural compound discovered in 1965 from an extract of yew tree (Taxus Brevifolia Nutt.)....
2003 Spring.Includes bibliographical references.The exploration of several strategies for the synthe...
Taxol®, isolated from the bark of the Pacific yew tree (Taxus brevifolia Nutt.), is a very effective...
A highly functionalized intermediate in the synthesis of Taxol has been synthesized, which features ...