High-Density Lipoprotein Cholesterol and Cardiovascular Events in Patients with Stable Coronary Artery Disease Treated with Statins : An Observation from the REAL-CAD Study
- Omote, Kazunori
- Yokota, Isao
- Nagai, Toshiyuki
- Sakuma, Ichiro
- Nakagawa, Yoshihisa
- Kamiya, Kiwamu
- Iwata, Hiroshi
- Miyauchi, Katsumi
- Ozaki, Yukio
- Hibi, Kiyoshi
- Hiro, Takafumi
- Fukumoto, Yoshihiro
- Mori, Hiroyoshi
- Hokimoto, Seiji
- Ohashi, Yasuo
- Ohtsu, Hiroshi
- Ogawa, Hisao
- Daida, Hiroyuki
- Iimuro, Satoshi
- Shimokawa, Hiroaki
- Saito, Yasushi
- Kimura, Takeshi
- Matsuzaki, Masunori
- Nagai, Ryozo
- Anzai, Toshihisa
DOIAbstract
Aim: The association between high-density lipoprotein cholesterol (HDL-C) level after statin therapy and cardiovascular events in patients with stable coronary artery disease (CAD) remains unclear. Thus, in this study, we sought to determine how HDL-C level after statin therapy is associated with cardiovascular events in stable CAD patients. Methods: From the REAL-CAD study which had shown the favorable prognostic effect of high-dose pitavastatin in stable CAD patients with low-density lipoprotein cholesterol (LDL-C) <120 mg/dL, 9,221 patients with HDL-C data at baseline and 6 months, no occurrence of primary outcome at 6 months, and reported non-adherence for pitavastatin, were examined. The primary outcome was a composite of cardiovascula...
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