Effectiveness of tumor necrosis factor α blockers in early axial spondyloarthritis: data from the DESIR cohort.
- Moltó, Anna
- Paternotte, Simon
- Claudepierre, Pascal
- Breban, Maxime
- Dougados, Maxime
DOIAbstract
International audienceTo estimate the frequency of use and effectiveness in daily practice of tumor necrosis factor α (TNFα) blockers in a population with inflammatory back pain suggestive of early axial spondyloarthritis (SpA). The Devenir des Spondylarthropathies Indifférenciées Récentes (DESIR) cohort is a prospective, multicenter, observational cohort of 708 patients with early (<3 years' duration) inflammatory back pain suggestive of axial SpA. The percentage of patients receiving TNFα blockers over the first 2 years of followup was estimated by survival analysis. To evaluate effectiveness, the primary outcome (40% improvement in disease activity according to the Assessment of SpondyloArthritis international Society criteria [ASAS40]) ...
Add to ORKG