Tryptophan and its bioactive metabolites are associated with health conditions such as systemic inflammation, cardiometabolic diseases, and neurodegenerative disorders. There are dynamic interactions among metabolites of tryptophan. The interactions between metabolites, particularly those that are strong and temporally reproducible could be of pathophysiological relevance. Using a targeted metabolomics approach, the concentration levels of tryptophan and 18 of its metabolites across multiple pathways was quantified in 24-hours urine samples at 2 time-points, age 17 years (baseline) and 18 years (follow-up) from 132 (52% female) apparently healthy adolescent participants of the DOrtmund Nutritional and Anthropometric Longitudinally Designed ...
Amino acid metabolites in biofluids are associated with high body mass index (BMI) and cardiometabol...
BackgroundThe tryptophan-kynurenine (KYN) pathway is linked to obesity-related systemic inflammation...
In recent decades, neuropsychiatric disorders such as major depressive disorder, schizophrenia, bipo...
Tryptophan and its bioactive metabolites are associated with health conditions such as systemic infl...
Serotonin and kynurenine are formed following metabolism of the essential amino acid tryptophan. Bot...
Tryptophan and tyrosine metabolism has a major effect on human health, and disorders have been assoc...
Crosstalk between the gut microbiome and the host plays an important role in animal development and ...
In addition to various physiologic roles, emerging evidence strongly points to pathogenic roles of t...
L-Tryptophan is the unique protein amino acid (AA) bearing an indole ring: its biotransformation in ...
Thesis (Ph.D.)--Boston UniversityTryptoPhan and its metabolites have been implicated in various ment...
Background: Tryptophan breakdown is an important mechanism in several diseases e.g. inflammation and...
Tryptophan is an essential amino acid that can be metabolised through different pathways, a major ro...
The modulation of host and dietary metabolites by gut microbiota (GM) is important for maintaining c...
Tryptophan is an essential amino acid that can be metabolised through different pathways, a major ro...
Background: During development of cardiovascular disease (CVD), interferon-γ-mediated inflammation a...
Amino acid metabolites in biofluids are associated with high body mass index (BMI) and cardiometabol...
BackgroundThe tryptophan-kynurenine (KYN) pathway is linked to obesity-related systemic inflammation...
In recent decades, neuropsychiatric disorders such as major depressive disorder, schizophrenia, bipo...
Tryptophan and its bioactive metabolites are associated with health conditions such as systemic infl...
Serotonin and kynurenine are formed following metabolism of the essential amino acid tryptophan. Bot...
Tryptophan and tyrosine metabolism has a major effect on human health, and disorders have been assoc...
Crosstalk between the gut microbiome and the host plays an important role in animal development and ...
In addition to various physiologic roles, emerging evidence strongly points to pathogenic roles of t...
L-Tryptophan is the unique protein amino acid (AA) bearing an indole ring: its biotransformation in ...
Thesis (Ph.D.)--Boston UniversityTryptoPhan and its metabolites have been implicated in various ment...
Background: Tryptophan breakdown is an important mechanism in several diseases e.g. inflammation and...
Tryptophan is an essential amino acid that can be metabolised through different pathways, a major ro...
The modulation of host and dietary metabolites by gut microbiota (GM) is important for maintaining c...
Tryptophan is an essential amino acid that can be metabolised through different pathways, a major ro...
Background: During development of cardiovascular disease (CVD), interferon-γ-mediated inflammation a...
Amino acid metabolites in biofluids are associated with high body mass index (BMI) and cardiometabol...
BackgroundThe tryptophan-kynurenine (KYN) pathway is linked to obesity-related systemic inflammation...
In recent decades, neuropsychiatric disorders such as major depressive disorder, schizophrenia, bipo...