Market regulators around the world are still debating whether high-frequency trading (HFT) plays a positive or negative role in market quality. We develop an artificial futures market populated with high-frequency traders (HFTs) and institutional traders using Strongly Typed Genetic Programming (STGP) trading algorithm. We simulate real-life futures trading at the millisecond time frame by applying STGP to E-Mini S&P 500 data stamped at the millisecond interval. A direct forecasting comparison between HFTs and institutional traders indicate the superiority of the former. We observe that the negative implications of high-frequency trading in futures markets can be mitigated by introducing a minimum resting trading period of less than 50 mill...