DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome.

Mercer, JR
Cheng, KK
Figg, N
Gorenne, I
Mahmoudi, M
Griffin, J
Vidal-Puig, A
Logan, A
Murphy, MP
Bennett, M

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Publication date

January 2020

DOI

10.1161/CIRCRESAHA.110.218966

Publisher

Ovid Technologies (Wolters Kluwer Health)

Journal

Circulation Research

Abstract

DNA damage is present in both genomic and mitochondrial DNA in atherosclerosis. However, whether DNA damage itself promotes atherosclerosis, or is simply a byproduct of the risk factors that promote atherosclerosis, is unknown

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DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome.

Abstract

Extracted data

DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome.

Abstract

Extracted data

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