Background: Multiple lines of evidence suggest that the onset and course of bipolar disorder is influenced by environmental light conditions. Increased suppression of melatonin by light (supersensitivity) in patients with bipolar disorder has been postulated as an endophenotype by several studies. However, due to methodological shortcomings, the results of these studies remain inconclusive. This study investigated melatonin suppression in euthymic patients with bipolar I disorder using evening blue light specifically targeting the melanopsin system. Methods: Melatonin suppression was assessed in euthymic patients with bipolar I disorder and healthy controls by exposure to monochromatic blue light (λmax = 475 nm; photon density = 1.6 × 10¹...
Life in 24-h society relies on the use of artificial light at night that might disrupt synchronizati...
Objectives: Pre-sleep exposure to especially short-wavelength light (i.e., 460–480 nm) acutely suppr...
Objectives/Introduction: Exposure to evening light from displays elicits changes in sleep and circad...
Objective:Among potential endophenotypes proposed for bipolar affective disorder focusing on circadi...
Among potential endophenotypes proposed for bipolar affective disorder focusing on circadian abnorma...
Both dim and bright light has been shown to suppress the nocturnal secretion of the pineal hormone m...
It is well known that the pineal hormone melatonin is suppressed by light. The melatonin suppression...
Melatonin sensitivity to light in monozygotic twins discordant for bipolar I disorder [1
Sensitivity of the pineal hormone melatonin to bright light at night has been posited as a putative ...
Light is involved in providing entrainment of circadian rhythms and the suppression of the pineal ho...
Sensitivity of the pineal hormone melatonin to bright light at night has been proposed as a putative...
Patients with bipolar disorder have been shown to have a supersensitive melatonin suppression to dim...
Blue light sensitivity of melatonin suppression and subjective mood and alertness responses in human...
The super-sensitivity of the neurohormone melatonin to light in patients with bipolar disorder provi...
\u3cp\u3eThe short-wavelength (blue) light sensitivity of human circadian, neurobehavioral, neuroend...
Life in 24-h society relies on the use of artificial light at night that might disrupt synchronizati...
Objectives: Pre-sleep exposure to especially short-wavelength light (i.e., 460–480 nm) acutely suppr...
Objectives/Introduction: Exposure to evening light from displays elicits changes in sleep and circad...
Objective:Among potential endophenotypes proposed for bipolar affective disorder focusing on circadi...
Among potential endophenotypes proposed for bipolar affective disorder focusing on circadian abnorma...
Both dim and bright light has been shown to suppress the nocturnal secretion of the pineal hormone m...
It is well known that the pineal hormone melatonin is suppressed by light. The melatonin suppression...
Melatonin sensitivity to light in monozygotic twins discordant for bipolar I disorder [1
Sensitivity of the pineal hormone melatonin to bright light at night has been posited as a putative ...
Light is involved in providing entrainment of circadian rhythms and the suppression of the pineal ho...
Sensitivity of the pineal hormone melatonin to bright light at night has been proposed as a putative...
Patients with bipolar disorder have been shown to have a supersensitive melatonin suppression to dim...
Blue light sensitivity of melatonin suppression and subjective mood and alertness responses in human...
The super-sensitivity of the neurohormone melatonin to light in patients with bipolar disorder provi...
\u3cp\u3eThe short-wavelength (blue) light sensitivity of human circadian, neurobehavioral, neuroend...
Life in 24-h society relies on the use of artificial light at night that might disrupt synchronizati...
Objectives: Pre-sleep exposure to especially short-wavelength light (i.e., 460–480 nm) acutely suppr...
Objectives/Introduction: Exposure to evening light from displays elicits changes in sleep and circad...