The diploma thesis deals with the issue of digital commissioning of robotic operation of CNC machine tools. In the research part, individual types of industrial robots are analysed, including their advantages and disadvantages for the given application. Furthermore, several software used for digital commissioning are described and the possibilities of communication between machine tools and robots are described. In the practical part, a model task of operating two CNC machines is created. A suitable robot, robot tools, part magazines are selected, and a 3D model of the entire workplace is processed. In the final part, both a program for the robot and a program for the PLC controlling the entire workplace will be created