Therapy of diabetes mellitus and its possible complications

Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Mgr. Lenka Durasová Abstract Therapy of diabetes mellitus and its possible complications The aim of this thesis is to describe and explain the therapy and possible complications of diabetes mellitus. My document also includes a few interesting case reports belonging to this topic. Diabetes mellitus is a chronic condition that occurs when the pankreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. Hyperglycemia and other related disturbances in the body's metabolism can lead to serious damage to many of the body's systems, especiallity the nerves and blood vessels. A diabetes epidemic is underway. At least 171 million people worldwide have diabetes. This figure is likely to be more than double by 2030. Around 3,2 million deaths every year are attributable to complications of diabetes. Diabetes has become one of the major causes of premature illness and deth in most countries, mainly through the increased risk of cardiovascular disease. There are two basic forms of diabetes: Type 1 - people with this type of diabetes produce very little or no insulin. People with type 1 diabetes require daily injections of insulin to survive. Type 2 - people with this..