Physiological Principle of Neurorehabilitation : Diffuse Cerebral Hypoxia

OF BACHELOR THESIS Title: Physiological principle of neurorehabilitation Subtitle: Diffuse cerebral hypoxia Abstract of Bachelor thesis: This experimental work deals with the verification of a hypothesis that secondary brain changes induced by hypoxia can be influenced by neurorehabilitation. The aim is to determinate the effect of motor training in combination with erythropoietin and enriched environment on the functional state of a rat brain after hypoxia. The research subjects was 31 laboratory rats who were exposed to an altitude of 8,000 meters above sea level in hypobaric chamber, which induced diffuse cerebral hypoxia. The studied group of rats was subjected to regular motor training and was compared with the control group which underwent the rehabilitation without motor training. The experiment lasted 8 weeks and took place at the Institute of Physiology, First Faculty of Medicine. Results of the study showed improvement in the functional status of rats that were living in an enriched environment, were applied erythropoietin and underwent daily motor training. The increasing incidence of people who survive brain damage, connected with an oxygen deficiency, increases the importance of monitored dependencies between the neurorehabilitation and the functional state of the organism. The..