Non-coding RNA in hepresvirus infection

MiRNAs are endogenous short RNAs that are well conserved in eukaryotic organisms and are thought to be a vital and evolutionarily ancient component of genetic regulation. Their key role is in post-transcriptional regulation of gene expression. Some viruses were able to utilize the capabilities of these tiny RNAs to regulate their own gen expression or to regulate host gene expression in use of avoidance from immunity answers to their presence. Among these viruses belongs also the Herpesviridae family. Members of this family are using miRNA in various ways, from regulation of their own gene expression to targeting host mRNA, which prevents translation of factors related to immune answers. This work is intent on biogenesis of miRNA, its mechanism, function and manner in which it is used by representatives from Herpesviridae family