Feasibility of Non-Pharmacological Intervention in Therapy of Cognition Deficit in Czech Schizophrenia Patients - Computer-assisted Cognitive Remediation

There is a body of scientific literature describing cognitive deficit in schizophrenia and the possibility of its remediation. However, in the Czech Republic, there have been so far just few studies that examined the topic. The objective of this work was to explore the feasibility of non-pharmacological intervention in the form of computer-assisted cognitive remediation of Czech schizophrenia patients with diagnosed cognitive deficit. Our results confirmed the positive short-term effect of targeted remediation of selective domains of cognitive deficit in patients with schizophrenia. Our findings suggested that 5 working memory function is the domain most sensitive to the structured intervention. These results are consistent not only with findings from other published studies that used similar computer method for remediation, but also with other studies that used different approaches. In addition, working memory function improved in the generalized form (visual intervention improved auditive function). Key words: Schizophrenia, cognition, deficit, remediation, compute