MenB vaccine uptake and number of reported cases with MenB infection

MenB vaccine uptake and number of reported cases with MenB infection Author: Monika Švédová Supervisor: PharmDr. Eva Zimčíková, Ph.D. Department of Social and Clinical Pharmacy Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Meningococcal disease caused by Neisseria meningitidis is global issue and it's known for its epidemical potential. In Europe, this disease is most often caused by B and C serotype. Main aim was to track occurence and other epidemiologic aspects related to invasive meningococcal disease (IMD) in the Czech Republic from 2007 to 2016, focusing on serotype B and summarize available vaccinations which are used to fight disease mentioned above. Another was to analyse usage of Bexsero vaccination in the Czech Republic, hand in hand with number of spontaneous reports of adverse events after vaccination. Methodology: To assess epidemiologic aspects related to IMD data from the Centre of epidemiology and microbiology were used (years 2007 - 2016). Vaccination utilization was analysed based on data from the State Institue of Drug Control and expressed as number of packages. Central database of spontaneous adverse events reports was used to determine number and character of reports. Results: In period 2007-2016 there was a decrease in meningococcal disease..