Add to ORKGThe topic of the presented thesis is the regulation of gene expression level of the three HSP70 genes in mononuclear cells. We investigated the dependence of expression regulation (induction) abiliy on selected point mutations, so-called SNPs (single nucleotide polymorphism) in the observed genes. The mononuclear cells were obtained from peripheral blood samples of healthy individuals. In order to analyze their gene expression, we selected individuals who were homozygous for at least one of the monitored point mutations. Taking into account the chosen criteria for healthy individuals we based on interviews with these individuals and their personal history. We determined the polymorphisms observed in two cell stress-inducible HSP70-1 (HSPA1A...
The human heat shock protein 70 (hsp70) gene is expressed constitutively in a wide variety of cells....
Expression of the human heat shock protein 70 gene (hsp70) is induced by various kinds of stress and...
Acclimatization is a process which occurs as a result of repeated mild increases in core temperature...
The topic of the presented thesis is the regulation of gene expression level of the three HSP70 gene...
The regulation of heat shock protein expression is of significant physiological and pathophysiologic...
(Abstract) Some of heat shock proteins (Hsp), for example the inducible form Hsp70, are expressed on...
(Abstract) Some of heat shock proteins (Hsp), for example the inducible form Hsp70, are expressed on...
MHC complex is the most polymorphic, most complex and one of the most important parts of a genome wh...
MHC complex is the most polymorphic, most complex and one of the most important parts of a genome wh...
The identification of human sequence polymorphisms that regulate gene expression is key to understan...
The expression of a hsp70 gene in human cells has previously been shown to be related to the growth ...
The expression of a hsp70 gene in human cells has previously been shown to be related to the growth ...
Expression of the human heat shock protein 70 gene (hsp70) is induced by various kinds of stress and...
Introduction: The epigenetic modifications can significantly affect and alter the gene activity by r...
This is an Open Access article distributed under the terms of the Creative Common
The human heat shock protein 70 (hsp70) gene is expressed constitutively in a wide variety of cells....
Expression of the human heat shock protein 70 gene (hsp70) is induced by various kinds of stress and...
Acclimatization is a process which occurs as a result of repeated mild increases in core temperature...
The topic of the presented thesis is the regulation of gene expression level of the three HSP70 gene...
The regulation of heat shock protein expression is of significant physiological and pathophysiologic...
(Abstract) Some of heat shock proteins (Hsp), for example the inducible form Hsp70, are expressed on...
(Abstract) Some of heat shock proteins (Hsp), for example the inducible form Hsp70, are expressed on...
MHC complex is the most polymorphic, most complex and one of the most important parts of a genome wh...
MHC complex is the most polymorphic, most complex and one of the most important parts of a genome wh...
The identification of human sequence polymorphisms that regulate gene expression is key to understan...
The expression of a hsp70 gene in human cells has previously been shown to be related to the growth ...
The expression of a hsp70 gene in human cells has previously been shown to be related to the growth ...
Expression of the human heat shock protein 70 gene (hsp70) is induced by various kinds of stress and...
Introduction: The epigenetic modifications can significantly affect and alter the gene activity by r...
This is an Open Access article distributed under the terms of the Creative Common
The human heat shock protein 70 (hsp70) gene is expressed constitutively in a wide variety of cells....
Expression of the human heat shock protein 70 gene (hsp70) is induced by various kinds of stress and...
Acclimatization is a process which occurs as a result of repeated mild increases in core temperature...