Reproductive ageing and multiple births

Reproductive ageing and multiple births Abstract This diploma thesis is focused on the occurrence of double births in connection with the issue of postponing the fertility of women into old age. The aim of the work is to evaluate the influence of the increasing age of mothers at the birth of a child and the development of methods of assisted reproduction on the increase in the proportion of multiple births in the Czech Republic. Furthermore, to find out the differences or similarities between children born from single and multiple pregnancies in terms of socio-demographic characteristics of mothers. Based on publicly available data from the CZSO, the development of fertility was outlined, as well as the development of multiple births in the years 1950-2019. The extent to which maternal age contributes to the incidence of double pregnancies and the extent to which it is affected by the use of assisted reproduction methods was estimated using the method of direct standardization. Based on anonymized individual data from the NRROD in 2018, the chances of a double birth were estimated using the binary logistic regression method, depending on the age of the mothers and other characteristics. Multiple pregnancies are the greatest risk of assisted reproduction and can cause serious health complications, especially..