Feynman diagrams constitute one of the essential ingredients for making precision predictions for collider experiments. Yet, while the simplest Feynman diagrams can be evaluated in terms of multiple polylogarithms -- whose properties as special functions are well understood -- more complex diagrams often involve integrals over complicated algebraic manifolds. Such diagrams already contribute at NNLO to the self-energy of the electron, $t \bar{t}$ production, $\gamma \gamma$ production, and Higgs decay, and appear at two loops in the planar limit of maximally supersymmetric Yang-Mills theory. This makes the study of these more complicated types of integrals of phenomenological as well as conceptual importance. In this white paper contributio...