Chronic obstructive pulmonary disease: pathophysiology and physiotherapeutic approach

Kronična opstruktivna bolest pluća (KOPB) kronična je bolest koja nastaje opstruktivnim oštećenjem pluća koje izaziva promjene u strukturi plućnog parenhima i dišnih puteva. Strukturne promjene nastaju zbog upale te uzrokuju opstrukciju dišnih puteva. Za smanjenje učestalosti, težine egzercebacija i smrtnosti oboljelih od KOPB-a zaslužno je liječenje sistemske upale u kroničnoj opstruktivnoj bolesti pluća. Cilj je ovog preglednog rada predstaviti KOPB kao učestalu bolest 21. stoljeća s visokom smrtnošću, definirati bolest i prikazati njenu kliničku sliku, patofiziologiju i etiologiju, način dijagnosticiranja, liječenje i fizioterapijsku rehabilitaciju.Chronic obstructive pulmonary disease (COPD) is a chronic disease caused by obstructive lung damage that causes changes in the structure of the lung parenchyma and airways. Structural changes occur due to inflammation and cause airway obstruction. The treatment of systemic inflammation in chronic obstructive pulmonary disease is responsible for reducing the incidence, severity of exacerbations and mortality of COPD patients. The aim of this review article is to present COPD as a common disease of the 21st century with high mortality, to define the disease and to present its clinical picture, pathophysiology and etiology, method of diagnosis, treatment and physiotherapeutic rehabilitation