A study of lipid profile (total cholesterol, tgl, ldl) among clinical hypothyroids and subclinical hypothyroids

Background: Thyroid diseases are the commonest endocrine disorders in the world. Thyroid hormones are among the most imperative humoral factors involved in setting the basal metabolic rate on a long rate on a long term basis in target tissues such as liver, heart. Kidney and brain. The prevalence of subclinical thyroid dysfunction is higher than that of overt thyroid dysfunction. In general hypothyroidism is associated with hyper cholesterolemia mainly due to elevation of LDL –C levels. This study was done on the lipid profile among clinical and sub clinical hypothyroids. Materials and methods: A total of 400 subjects were analyzed to get a total of 50 clinical hypothyroids pts; 50 subclinical and 50 healthy individuals based on their thyroid profile and detailed history. Patients were taken from outpatient department at KIMS and RF with respect to inclusion and exclusion criteria and lipid profile was measured. Results: In hypothyroidism, it was observed that in hypothyroidism, there is hypercholesterolemia, increased triglycerides and LDL levels which is more in clinical hypothyroids compared to subclinical hypothyroids. Conclusion: We conclude that hypothyroidism causes worsening of dyslipidemia, more in clinical hypothyroid than in subclinical hypothyroid patients