Randomized controlled trial to determine analgesic efficacy of intrathecal 1% 2- chloroprocaine with or without fentanyl during elective caesarean section

Background-Preservative free 1% 2‑chlorprocaine is a short acting local anaestheticagent appropriate for day care surgical techniques. Potentiation of analgesic accomplishment of intrathecal local anesthetics by the addition of opioids is well recognized. Objectives- To investigate the effect of intrathecal fentanyl as an adjuvant to 1% 2‑chloroprocaine (2‑CP) in parturients undergoing elective lower segment caesarean section (LSCS). Methods: A prospective randomized double blindstudy was performed on 150 healthy, term parturients planned for elective LSCS, divided into two equal groups. The group C1 received 1% preservative‑free 2‑CP 3 ml (30 mg) + 0.5 ml normal saline and group C2 received 1% preservative‑free 2‑CP 3 ml (30 mg) + 0.5 ml fentanyl (25 μg) with a total volume of 3.5 ml intrathecally in both groups. The duration of sensory blockade, duration of motor blockade, maximum height of sensory block, haemodynamic parameters, quality of block, neonatal outcome, patient satisfaction and any side effects were recorded. Results: There were no significant differences in demographic characteristics, haemodynamic parameters, onset of sensory block, and onset of motor block and duration of motor block between the groups.&nbsp