A clinico-pathological study of primary intracranial neoplasms in a tertiary care hospital

Background: Central nervous system neoplasms represent a   unique, heterogeneous population of neoplasms and include both benign and malignant  tumours. The tumours of central nervous system are reported to be less than 2% of all malignancies. Aim: To study the frequency of intracranial tumours and their histopathological typing and their correlation with several clinical variables such as age, sex and clinical symptoms . Material & Methods: Study Design: Hospital based Prospective observational study. Study area: Dept. of. Pathology, Study Period: 2 years. Study population: patients who presented with signs and symptoms of primary intracranial tumours were examined and followed up for the histopathological diagnosis. Sample size: Study population consisted a total of 68 patients.  Sampling method: Simple Random sampling method. Inclusion criteria: Patients with both benign as well as malignant primary neoplasms of the brain including pituitary tumours. Exclusion criteria: All the spinal cord, calvarial and metastatic tumours were excluded. Ethical consideration: Institutional Ethical committee permission was taken prior to the commencement of the study. Study tools and Data collection procedure: Staining Procedures Adopted: After grossing, proper tissue bits were subjected for routine processing, fixation, dehydration, clearing and embedding in paraffin wax and blocks were made.&nbsp