Correlation between glycosylated haemoglobin and serum lipid profile in patients with type 2 diabetes mellitus in a Tertiary Care Hospital

Type 2 diabetes mellitus (T2DM) is a chronic disease that develops due to defective insulin secretion and is frequently associated with insulin resistance. T2DM patients are prone to diabetic dyslipidemia, which puts them at risk of developing macrovascular (stroke, peripheral vascular disease and coronary artery disease) and microvascular (nephropathy, neuropathy and retinopathy) diseases. This is a cross sectional study conducted at Tertiary care Teaching Hospital over a period of 1 year. Total 70 patients of Type 2 diabetes mellitus were taken for the study after applying inclusion and exclusion criteria, and after obtaining written and informed consent from them. HbA1c and Fasting Lipid profile: Total cholesterol, Triglycerides, HDL and VLDL cholesterol were measured. In our study, among 70 Type 2 diabetic individuals included in this study, 41 were male and 29 were female. Distribution of Glucose Triad results of FBS, PPBS and HbA1c levels of patients presented as Mean±SD, mean FBS was 173.59±39.64, mean PPBS was 234.59±94.59 and mean HbA1c was 7.78±0.83. Our study accomplished that HbA1c has a direct, significant correlation with total cholesterol, triglyceride, VLDL, and LDL among the lipid profile