Comparative evaluation demineralized freeze dried bone allograft with and without platelet rich fibrin in intrabony defects: A clinical and radiographical study

Background and Objectives: The study was designed to evaluate the clinical and radiological effectiveness of demineralized freeze dried bone allograft with and without platelet rich fibrin in intrabony defects. Materials and Methods: twelve patients with 2 intrabony defects were recruited for the study. The two defects in each patient were randomly assigned to receive either DFDBA (site A) or DFDBA with PRF (site B). Soft tissue measurements and radiographs were taken at baseline, 3, 6 and 9 months. Results: The results indicated that probing depths were reduced by 3.08 ± 1.16 mm at site A and 3.33 ± 1.72 mm at site B.  Site A resulted in 2.42 ± 1.24mm attachment gain, while site B had a 3.17 ± 1.40 mm gain in attachment Site A. Defects displayed 2.00mm bone fill. Site B defects showed 3.00 mm bone fill. Both treatments provided soft and hard tissue improvement when compared to baseline. No statistical significance was noted between the two groups. Conclusion: The Clinical evaluation is suggestive of the fact that both DFDBA and PRF are biocompatible with the tissues