It is most generally admitted that seimic ground motion is the convolution of source, path and site effects. The question addressed here is whether a fourth term, called "Site-City Interaction" (SCI), should be added for densely urbanized areas, corresponding to feedback effects from the shaken buildings in the soil. After a short overview of various, consistent observations, several specific experimental and numerical results are briefly summarized, that clearly evidence the wave radiation from isolated buildings and the possibilty of interactions between close buildings as well. The seismic response of a simple "city model" represented by a group of buildings is then addressed through a series of numerical simulations, which allow to dete...