Hot collisional orogens are characterized by abundant syn-kinematic granitic magmatism that profoundly affects their tectono-thermal evolutions. Voluminous granitic magmas, emplaced between 360 and 270 Ma, played a visibly important role in the evolution of the Variscan Orogen. In the Limousin region (western Massif Central, France), syntectonic granite plutons are spatially associated with major strike-slip shear zones that merge to the northwest with the South Armorican Shear Zone. This region allowed us to assess the role of magmatism in a hot transpressional orogen. Microstructural data and U/Pb zircon and monazite ages from a mylonitic leucogranite indicate synkinematic emplacement in a dextral transpressional shear zone at 313 +/- 4 M...