Study on diagnostic accuracy of fine needle aspiration cytology in different breast lesion and histopathological correlation

Introduction -FNAC is being performed as a pre-operative test to evaluate breast lump. FNAC is cost effective and can prevent unnecessary surgery. As FNAC became more reliable in diagnosing malignancy .Confirmation of breast diseases by clinical examination and pathological confirmation by fine needle aspiration cytology (FNAC) and histopathologic examination has been found to be an important part of diagnostic workup in breast diseases. Material and method-A retrospective study done on119 cases presented with history of palpable breast lumpduringNovember 2019 to October 2020 in department of pathology Government Medical College Shivpuri, India. All female patients were included of age 11-70 year, irrespective of their, religion, marital status, occupation or social status. Every patient underwent a FNAC done on OPD basis by a trained pathologist from the Pathology Department, histopathology was available in 54 cases for correlation with cytology. Result- Results of all patients were collected and tabulated. Statistical analysis was performed on the tabulated data and sensitivity and specificity with positive and negative predictive value were obtained. Maximum cases(54.1%)of benign lesion as fibroadenoma were diagnosed in age group of 21-30 years and malignant cases (80%) were diagnosed 51-60 years. The sensitivity and specificity and diagnostic accuracy for malignancy were found to be 95%,97% And 94.5%, respectively. Conclusion- FNAC serves as a rapid, economical, and reliable tool for the diagnosis of palpable breast lesions because the cytopathological examination of these lesions before operation or treatment, serves as an important diagnostic tool. Most common breast lesion in this study is fibroadenoma