Modified Left Ventricle Fetal Myocardial Performance Index: A cross sectional study in a tertiary care hospital

Introduction: Modified left ventricular fetal myocardial performance index (MPI) is a pulse wave Doppler index that can be utilized to assess global fetal myocardial function. Fetal MPI is handily performed non- invasive method for the assessment of foetal cardiovascular well-being.Aim: This study aimed to access normal values for foetal modified left ventricular (LV) MPI and its correlation with heart rate and gestational age among foetuses in central india.Material and Method: This cross sectional study was conducted in department of Radio-diagnosis from January 2020 to December 2020. In our study, total seventy one singleton pregnant women with normal pregnancy were included. The Mod-LV MPI was calculated as the ratio of sum of the isovolumetric constriction time (ICT) and isovolumetric relaxation time (IRT) upon ejection time (ET). MPI = ICT+IRT/ ET. We also assessed correlation of MPI with foetal heart rate and gestational age. SPSS Statistics software version 20 was used for the statistics analysis.Results: The normal mean MPI of second and third trimester fetuses of Indian population was 0.409±0.052. Mean ICT was 45.7 ± 7.0ms, mean IRT was 55.9 ± 6.7ms, and mean ET was 148.2 ± 10ms. The mean FHR was 142.26 ± 5.8 bpm and mean gestation age (weeks) is 33.16 ± 4.8. The coefficient correlation (r) between MPI and gestational age was 0.017 and that between MPI and heart rate was 0.030 suggesting MPI is independent of both gestational age and FHR. Conclusion: Our study gives the normal range of MPI in the normal heart foetuses of the Indian population, and it also shows that MPI is independent of gestational age and FHR. MPI has role in subclinical foetal cardiovascular malfunction and intrauterine foetal cardiovascular monitoring for foetal wellbeing