Add to ORKGResearch has led to the development of tailored treatment options for different cancers in different patients. Despite some treatments being able to provide remarkable responses, nearly all current treatments encounter the same issue: resistance. Here, we discuss our experiences with how breast cancers resist therapies. The focus of our discussion revolves around the cancer stem cell subpopulation and their mechanisms for resistance
International audienceThere is growing evidence for the role of cancer stem-cells in drug resistance...
Introduction: Several reports have suggested that a population of undifferentiated cells known as ca...
Drug resistance represents one of the greatest challenges in cancer treatment. Cancer stem cells (CS...
Research has led to the development of tailored treatment options for different cancers in different...
The clinical and pathologic heterogeneity of human breast cancer has long been recognized. Now, mole...
The clinical and pathologic heterogeneity of human breast cancer has long been recognized. Now, mole...
PurposeThe lethal effects of cancer are associated with the enhanced tumor aggressiveness in recurre...
Resistance to tumor therapy is an unsolved problem in cancer treatment. A plethora of studies have a...
Abstract Some cancers like melanoma and pancreatic and ovarian cancers, for example, c...
About 20% of the total cells from primary breast tumors could generate palpable tumors in non-obese ...
Cancer is a heterogenous disease displaying marked inter- and intra- tumoral diversity. The existenc...
Triple Negative Breast Cancer (TNBC) is the most lethal subtype of breast cancer. Despite the succes...
Only a fraction of the cells in a breast tumour are able to seed new tumour growth. These so-called ...
Breast cancer cells are suggested to be organized in a hierarchical manner with a subpopulation of s...
International audienceThere is growing evidence for the role of cancer stem-cells in drug resistance...
Introduction: Several reports have suggested that a population of undifferentiated cells known as ca...
Drug resistance represents one of the greatest challenges in cancer treatment. Cancer stem cells (CS...
Research has led to the development of tailored treatment options for different cancers in different...
The clinical and pathologic heterogeneity of human breast cancer has long been recognized. Now, mole...
The clinical and pathologic heterogeneity of human breast cancer has long been recognized. Now, mole...
PurposeThe lethal effects of cancer are associated with the enhanced tumor aggressiveness in recurre...
Resistance to tumor therapy is an unsolved problem in cancer treatment. A plethora of studies have a...
Abstract Some cancers like melanoma and pancreatic and ovarian cancers, for example, c...
About 20% of the total cells from primary breast tumors could generate palpable tumors in non-obese ...
Cancer is a heterogenous disease displaying marked inter- and intra- tumoral diversity. The existenc...
Triple Negative Breast Cancer (TNBC) is the most lethal subtype of breast cancer. Despite the succes...
Only a fraction of the cells in a breast tumour are able to seed new tumour growth. These so-called ...
Breast cancer cells are suggested to be organized in a hierarchical manner with a subpopulation of s...
International audienceThere is growing evidence for the role of cancer stem-cells in drug resistance...
Introduction: Several reports have suggested that a population of undifferentiated cells known as ca...
Drug resistance represents one of the greatest challenges in cancer treatment. Cancer stem cells (CS...