Variations of coronary sinus tributaries among patients undergoing cardiac resynchronization therapy

Background: In cardiac resynchronization therapy, the coronary venous system is used for left ventricular pacing electrode placement. Despite the well-known anatomy of the coronary sinus and its tributaries, heart failure patients' remodeled and enlarged left ventricles may impede the successful lead placement because of acquired anatomical obstacles. Materials and methods: Fifty-five patients qualified for cardiac resynchronization therapy treatment (CRT) were divided into ischemic and non-ischemic cardiomyopathy. Forty-four control groups without heart failure underwent dual-source computed tomography (CT). Rendered reconstructions of cardiac coronary systems were compared. Results: The presence of main tributaries was comparable in all groups. The left marginal vein, small cardiac vein, and oblique vein of the left atrium were present in 63%, 60%, and 51% of the hearts in all the groups. CRT referred CT's had significantly longer distances between posterior and lateral cardiac veins over the left ventricle (p < 0.05), wider angles of tributaries (p = 0.03), and smaller lumen of coronary sinus (p = 0.03). In the non-ischemic group, the posterior interventricular and great cardiac veins are more extensive than in the control group. Age-related analysis of vessel size shows a moderate correlation between age and diminishing mean vessel size in all the groups studied. Conclusions: The general structure of the coronary heart system is consistent in patients with and without heart failure. The variance of the general structure, or the presence of adequate veins, is an individual variation. The use of CT and analysis of the coronary veins allow better planning of the CRT-D implantation procedure and may reduce the risk of ineffective left ventricular electrode implantation