Brugada syndrome: rare so, beware!

Brugada syndrome (BrS) is a rare disease, caused by mutations in the gene that encodes cardiac sodium channel and is characterized by ST-segment elevation in the right precordial leads of electrocardiogram (ECG). This channelopathy significantly increases the risk of sudden cardiac death (SCD) due to life-threatening ventricular arrhythmias in individuals with structurally normal hearts. In this case report, the authors present a 60 years-old male after an episode of presyncope, with no personal or familial history of cardiovascular disease, whose spontaneous resting ECG showed Brugada pattern, which was confirmed in a provocative drug test with ajmaline.Brugada syndrome (BrS) is an autosomal dominant channelopathy, caused by mutations in the cardiac sodium channel gene and characterized by ST-segment elevation in the right precordial leads of electrocardiogram (ECG). This condition is associated with significantly increased risk of malignant ventricular arrhythmias and sudden cardiac death (SCD) in individuals without structural heart disease. In this case report the authors present a 60 years-old male after an episode of presyncope, with no personal or familial history of cardiovascular disease, whose spontaneous resting ECG showed Brugada pattern, which was confirmed in a provocative drug test with ajmaline