Development and Evaluation of Poly Herbal Ointment for Wound Healing Activity

Wound healing is a complex and continuous process that begins immediately after injury, followed by homeostasis, blood clotting, inflammation, proliferation and remodeling phases. All these phases can promote or prolong healing by influencing external or internal factors including infection sex hormones and nutrition. Delay in healing process increases the possibility of getting infected, improper recovery, and formation of unpleasant scar. The study thus demonstrated the wound healing activity of methanolic extract of poly herbal ointment were found to be effective in the functional recovery of the wound. The extracts promote wound closure of excision wound as compared to control group. The result may be attributed to the phytoconstituents such as flavonoids and phenolics present in it which may be due to their enhanced wound healing and provided scientific evidence to the ethno medicinal futures of poly herbal formulations. The study concludes that the poly herbal extract obtained by the dried powders of Neem leaves, Tridax leaves, Aloe gel and Turmeric rhizome posses antimicrobial activity. Incorporation of the poly herbal extract into ointment base at 4% (F4) demonstrated ideal physiochemical characteristics. These findings could justify the inclusion of this formulations in the management of wound healing