Consequences of prematurity on cortisol regulation and adjustment difficulties ::a 9-year longitudinal study
- Urfer, Auriana
- Turpin, Hélène
- Dimitrova, Nevena
- Borghini, Ayala
- Plessen, Kerstin Jessica
- Morisod-Harari, Mathilde
- Urben, Sébastien
DOIAbstract
A preterm birth represents a stressful event having potentially negative long-term consequences. Thirty-three children born preterm (<33 weeks gestational age) and eleven full-term children participated in a nine-year longitudinal study. Perinatal Risk Inventory (PERI) was used at birth to assess the perinatal stress. Salivary cortisol, collected four times a day over two consecutive days, was measured with radioimmunoassay technique at six months and nine years to assess the hypothalamic-pituitary-adrenal (HPA) axis. Mothers reported post-traumatic symptoms on a self-report questionnaire 12 months after their child’s birth and children’s adjustment problems at 9 years of child age on the Child Behavior Checklist. Results showed a significa...
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