Emerging virus infections in adverse pregnancy outcomes ::Special Issue

Viruses that emerged in the past decades, such as arboviruses and SARS-coronaviruses, are increasingly recognized as potential risk factors for adverse pregnancy outcomes. On the fetal side, arboviruses have proved their ability to cross the placental barrier, at different stages of pregnancy, and have been associated with fetal losses, fetal malformations (Zika, West Nile, and Venezuelan equine encephalitis viruses) and adverse neonatal outcomes (Dengue and Chikungunya viruses). The SARS-COV-2 has also be associated with rare maternal-fetal transmission and placental affection leading to fetal losses. More common viruses, like cytomegalovirus, are also well-known causes of fetal and childhood sequelae, and recent research on its prognosis factors and in-utero treatment may be welcome. On the maternal side, SARS-COV-2 might compromise maternal health, as well as Dengue viruses have been associated with high risks of adverse obstetrical outcomes, including maternal death, pre-eclampsia or post-partum hemorrhage. Thus, research on the maternal physiopathology would also be welcome. In this Special Issue of Viruses, we aim for original researchs, reviews and commentaries that contribute to an improved understanding of viral infection of placenta and fetal cells, or that report on the maternal and fetal outcomes after an emerging viral infection during pregnancy