A critical review on Tarkshya Agada

Background: Agadatantra is one of the branches of Ashtanga Ayurveda, that consist of the science of poison (toxicology), which deals with different poisoning conditions, diagnosis, and treatment. Among all Vishas, Sarpavisha is most significant as it is the condition that needs emergency management. There are many Agada Yogas (anti-poisonous formulations) that are helpful in Sarpavisha Chikitsa mentioned by Ayurvedic Acharyas. Tarkshya Agada is one of the Agada Yogas mentioned by Acharya Susrutha in Susrutha Samhita and Acharya Vridda Vagbhata in Ashtanga Sangraha. Materials and Method: The comprehensive review of Tarkshya Agada formulation is done from literatures such as Susrutha Samhita and Ashtanga Sangraha, by emphasizing its properties and action. Observation and results: Tarkshya Agada explained by Acharya Susrutha has contains twenty-four drugs, and Acharya Vridda Vagbhata comprises twenty-five drugs, almost containing the same drugs whereas Acharya Susrutsa mentioned Balaka and Chandana, Acharya Vridda Vagbhata mentioned Shunti, Padmaka and Sita different drugs, all of which have Vishahara and Shothohara properties and can be used in the treatment of Sarpavisha. Conclusion: Tarkshya Agada mentioned by Acharya Susrutha and Acharya Vridda Vagbhata in Sarpavisha Chikitsa may be found to be one of the effective anti-poisonous formulations which should be tried for experimental and clinical trials in Sarpavisha Chikitsa