PAMAM and PPI dendrimers as potential anti-cancer drug carriers: a computational investigation
- Eric A. Zizzi
- Lorenzo Pallante
- Marcello Miceli
- Krzysztof Sztandera
- Mateusz Bątal
- Jacek A. Tuszynski
- Marco A. Deriu
Publication date
January 2021
DOI Publisher
Frontiers Media SA Language
EnglishAbstract
Photodynamic therapy (PDT) is a promising technique for several types of anti-cancer therapy, exploiting a photosensitizer, a light source and oxygen. The present work computationally investigates the properties of poly(amidoamine) (PAMAM) and poly(propyleneimine) (PPI) dendrimers of generation 3 and 4 as potential nanoscale drug delivery systems for Rose Bengal (RB), a candidate photosensitizer for PDT
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