The mammary gland undergoes apoptosis when estrogen ablation occurs, either naturally or enforced. The gland is known to execute the apoptotic process post weaning. Although the involuting mammary gland displays the characteristic biochemical features of apoptosis, including DNA fragmentation, chromatin condensation, and the formation of apoptotic bodies, it also shows evidence of an autophagic death. In this report, apoptosis of the gland was induced by removing the pups from their nursing mothers. In particular, we show that lysosomes increased in size and number, and moved from basal to apical regions in dying rat mammary gland cells. Lysosomal enzyme activities were significantly greater in degenerating mammary gland (day 4 post weaning...
Apoptosis is a form of cell death in which cellular integrity is maintained and neither cytoplasmic ...
Abstract Mammalian ovary contains millions of germ cells during embryonic life but only few of them ...
Epithelial cell survival is dependent on extracellular signals provided by both soluble factors and ...
Apoptosis programmed cell death (PCD) type I is physiological process responsible for cell loss dur...
Postlactational involution of the mammary gland is characterized by two distinct physiological event...
The role of cell death in involution of lactating breast was investigated in mice and rats by light ...
It is well established that lysosomes play an active role during the execution of cell death. A rang...
Ductal morphogenesis in the rodent mammary gland is characterized by the rapid penetration of the st...
It is well established that lysosomes play an active role during the execution of cell death(1). A r...
The mammary gland represents an unique model system to allow investigation of factors that underpin ...
Mammary gland involution is a physiological process that follows lactation and results in the rapid ...
Following the cessation of lactation, the mammary gland undergoes a physiologic process of tissue re...
Cell death is a process for maintaining homeostasis in tissues and organs. In the ovary, apoptotic c...
Apoptosis is essential to eliminate secretory epithelial cells during the involution of the mammary ...
Cells may use multiple pathways to commit suicide. In certain contexts, dying cells generate large a...
Apoptosis is a form of cell death in which cellular integrity is maintained and neither cytoplasmic ...
Abstract Mammalian ovary contains millions of germ cells during embryonic life but only few of them ...
Epithelial cell survival is dependent on extracellular signals provided by both soluble factors and ...
Apoptosis programmed cell death (PCD) type I is physiological process responsible for cell loss dur...
Postlactational involution of the mammary gland is characterized by two distinct physiological event...
The role of cell death in involution of lactating breast was investigated in mice and rats by light ...
It is well established that lysosomes play an active role during the execution of cell death. A rang...
Ductal morphogenesis in the rodent mammary gland is characterized by the rapid penetration of the st...
It is well established that lysosomes play an active role during the execution of cell death(1). A r...
The mammary gland represents an unique model system to allow investigation of factors that underpin ...
Mammary gland involution is a physiological process that follows lactation and results in the rapid ...
Following the cessation of lactation, the mammary gland undergoes a physiologic process of tissue re...
Cell death is a process for maintaining homeostasis in tissues and organs. In the ovary, apoptotic c...
Apoptosis is essential to eliminate secretory epithelial cells during the involution of the mammary ...
Cells may use multiple pathways to commit suicide. In certain contexts, dying cells generate large a...
Apoptosis is a form of cell death in which cellular integrity is maintained and neither cytoplasmic ...
Abstract Mammalian ovary contains millions of germ cells during embryonic life but only few of them ...
Epithelial cell survival is dependent on extracellular signals provided by both soluble factors and ...