International audienceThe specific recognition of carbohydrates by lectins plays a major role in many cellular processes. Galectin-1 belongs to a family of 15 structurally related beta-galactoside binding proteins that are able to control a variety of cellular events, including cell cycle regulation, adhesion, proliferation, and apoptosis. The three-dimensional structure of galectin-1 has been solved by x-ray crystallography in the free form and in complex with various carbohydrate ligands. In this work, we used a combination of two-dimensional NMR titration experiments and molecular-dynamics simulations with explicit solvent to study the mode of interaction between human galectin-1 and five galactose-containing ligands. Isothermal titratio...
Galectins are β-galactoside-binding proteins implicated in a myriad of biological functions. Despite...
Galectins are β-galactoside-binding proteins implicated in a myriad of biological functions. Despite...
AbstractGalectin-1, a member of the conserved family of carbohydrate-binding proteins with affinity ...
AbstractThe specific recognition of carbohydrates by lectins plays a major role in many cellular pro...
AbstractThe specific recognition of carbohydrates by lectins plays a major role in many cellular pro...
The interaction of human galectin-1 with a variety of oligosaccharides, from di-(N-acetyllactosamine...
233 p.Glycans are essential molecules that are ubiquitously found in every living cell. The interact...
The interaction of human galectin-8 and its two separate N-terminal and C-terminal carbohydrate reco...
The interaction of human galectin-1 with a variety of oligosaccharides, from di-(N-acetyllactosamine...
Galectin-3 is an adhesion/growth-regulatory protein with a modular design comprising an N-terminal t...
The product of p53-induced gene 1 is a member of the galectin family, i.e., galectin-7 (Gal-7). To m...
The product of p53-induced gene 1 is a member of the galectin family, i.e., galectin-7 (Gal-7). To m...
The product of p53-induced gene 1 is a member of the galectin family, i.e., galectin-7 (Gal-7). To m...
Galectin-3 is an adhesion/growth-regulatory protein with a modular design comprising an N-terminal t...
Galectin-3 is an adhesion/growth-regulatory protein with a modular design comprising an N-terminal t...
Galectins are β-galactoside-binding proteins implicated in a myriad of biological functions. Despite...
Galectins are β-galactoside-binding proteins implicated in a myriad of biological functions. Despite...
AbstractGalectin-1, a member of the conserved family of carbohydrate-binding proteins with affinity ...
AbstractThe specific recognition of carbohydrates by lectins plays a major role in many cellular pro...
AbstractThe specific recognition of carbohydrates by lectins plays a major role in many cellular pro...
The interaction of human galectin-1 with a variety of oligosaccharides, from di-(N-acetyllactosamine...
233 p.Glycans are essential molecules that are ubiquitously found in every living cell. The interact...
The interaction of human galectin-8 and its two separate N-terminal and C-terminal carbohydrate reco...
The interaction of human galectin-1 with a variety of oligosaccharides, from di-(N-acetyllactosamine...
Galectin-3 is an adhesion/growth-regulatory protein with a modular design comprising an N-terminal t...
The product of p53-induced gene 1 is a member of the galectin family, i.e., galectin-7 (Gal-7). To m...
The product of p53-induced gene 1 is a member of the galectin family, i.e., galectin-7 (Gal-7). To m...
The product of p53-induced gene 1 is a member of the galectin family, i.e., galectin-7 (Gal-7). To m...
Galectin-3 is an adhesion/growth-regulatory protein with a modular design comprising an N-terminal t...
Galectin-3 is an adhesion/growth-regulatory protein with a modular design comprising an N-terminal t...
Galectins are β-galactoside-binding proteins implicated in a myriad of biological functions. Despite...
Galectins are β-galactoside-binding proteins implicated in a myriad of biological functions. Despite...
AbstractGalectin-1, a member of the conserved family of carbohydrate-binding proteins with affinity ...