Metal-free Michael addition initiated multicomponent oxidative cyclodehydration route to polysubstituted pyridines from 1,3-dicarbonyls

International audienceA simple metal-free, step-economic and selective access to pyr- idines from readily available substrates is reported, involving a flexible4A ̊ molecularsievespromotedMichaeladditioninitiated domino three-component reaction between a 1,3-dicarbonyl, a Michael acceptor and a synthetic equivalent of ammonia