EGFR-activating mutations, DNA copy number abundance of ErbB family, and prognosis in lung adenocarcinoma

Clinical Characteristics, Tumor, Node, Metastasis Status, and Mutation Rate in Domain of Epidermal Growth Factor Receptor Gene in Serbian Patients with Lung Adenocarcinoma

Zaric, Bojan
Stojsic, Vladimir
Kovacevic, Tomi
Sarcev, Tatjana
Tepavac, Aleksandar
Jankovic, Radmila
Spasic, Jelena
Radosavljevic, Davorin
Zarogoulidis, Paul
Vukobradovic-Djoric, Nevena
Perin, Branislav

September 2014

ObjectiveMutation rate in domain of EGFR gene varies between populations of lung cancer patients. Pr...

EGFR exon 19 in-frame deletion and polymorphisms of DNA repair genes in never-smoking female lung adenocarcinoma patients

Yang, SY

[[sponsorship]]基因體研究中心[[note]]已出版;[SCI];有審查制度;不具代表性[[note]]http://gateway.isiknowledge.com/gateway/G...

Activating mutations within the EGFR kinase domain: a molecular predictor of disease-free survival in resected pulmonary adenocarcinoma.

김세규
김주항
김호근
문진욱
박무석
박인규
장준
정경영
조병철
최혜진

January 2009

PURPOSE: Although epidermal growth factor receptor (EGFR) tyrosine kinase (TK) mutations are highly ...

EGFR Gene Copy Number Gain is Related to High Tumor SUV and Frequent Relapse after Adjuvant Chemotherapy in Resected Lung Adenocarcinoma

Koh, Youngil
Jang, Bogun
Jeon, Yoon Kyung
Kim, Tae Min
Lee, Se-Hoon
Kim, Dong-Wan
Chung, Doo Hyun
Kim, Young Tae
Kim, Young Whan
Heo, Dae Seog

April 2011

Objective: The purpose of our study was to define the prognostic impact of increased copies of epide...

Genetic and epigenetic analysis of erbB signaling pathway genes in lung cancer

HOQUE MO
BRAIT M
ROSENBAUM E
PAL P
BEGUM S
DASGUPTA S
CARVALHO AL
AHRENDT SA
WESTRA WH
SIDRANSKY D.
POETA, Maria Luana

January 2010

Prognosis for patients with non-small cell lung cancer (NSCLC) is poor. The potential value of modu...

Relationship between EGFR expression, copy number and mutation in lung adenocarcinomas

Wu Shafei
Gao Jie
Zeng Xuan
Zhang Jing
Liang Zhiyong
Liu Tonghua

July 2010

Abstract Background This study was designed to investigate EGFR protein expression, EGFR copy number...

Clustered Genomic Alterations in Chromosome 7p Dictate Outcomes and Targeted Treatment Responses of Lung Adenocarcinoma with Egfr-Activating Mutations

袁新盛
Yuan, Shinsheng

July 2012

Purpose Although epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have been...

Targeted Next-Generation Sequencing Analysis Predicts the Recurrence in Resected Lung Adenocarcinoma Harboring <i>EGFR</i> Mutations

In Ae Kim
Jae Young Hur
Hee Joung Kim
Song Am Lee
Jae Joon Hwang
Wan Seop Kim
Kye Young Lee

July 2021

Targeted NGS, widely applied to identify driver oncogenes in advanced lung adenocarcinoma, may also ...

Prognostic and Predictive Value of Epidermal Growth Factor Receptor Tyrosine Kinase Domain Mutation Status and Gene Copy Number for Adjuvant Chemotherapy in Non-small Cell Lung Cancer

Tsao, Ming-Sound
Sakurada, Akira
Ding, Keyue
Aviel-Ronen, Sarit
Ludkovski, Olga
Liu, Ni
Maître, Aurélie Le
Gandara, David
Johnson, David H.
Rigas, James R.
Seymour, Lesley
Shepherd, Frances A.

January 2011

Purpose:Patients with non-small cell lung carcinoma with epidermal growth factor receptor (EGFR) mut...

Epidermal growth factor receptor mutation status in stage I lung adenocarcinoma with different image patterns

Hsu, KH

[[sponsorship]]基因體研究中心[[note]]已出版;[SCI];有審查制度;不具代表性[[note]]http://gateway.isiknowledge.com/gateway/G...

Comprehensive Analysis of Epidermal Growth Factor Receptor Gene Status in Lung Adenocarcinoma

Li, Chenguang
Sun, Yihua
Fang, Zhaoyuan
Han, Xiangkun
Fang, Rong
Zhang, Yang
Pan, Yunjian
Zhang, Wenjing
Ren, Yan
Ji, Hongbin
Chen, Haiquan

June 2011

Introduction:The epidermal growth factor receptor (EGFR) gene status including tyrosine kinase domai...

Increased epidermal growth factor receptor (EGFR) gene copy number is strongly associated with EGFR mutations and adenocarcinoma in non-small cell lung cancers: A chromogenic in situ hybridization study of 182 patients

Chang, JWC

[[abstract]]To evaluate the association of epidermal growth factor receptor (EGFR) gene copy number ...

Prognostic implication of EGFR gene mutations and histological classification in patients with resected stage I lung adenocarcinoma.

Chun-Yu Lin
Yen-Mu Wu
Meng-Heng Hsieh
Chih-Wei Wang
Ching-Yang Wu
Ying-Jen Chen
Yueh-Fu Fang

January 2017

The prognostic value of epidermal growth factor receptor (EGFR) mutations and the correlation betwee...

The Association of EGFR Mutations with Stage at Diagnosis in Lung Adenocarcinomas.

Jaeyoung Cho
Sun Mi Choi
Jinwoo Lee
Chang-Hoon Lee
Sang-Min Lee
Jae-Joon Yim
Doo Hyun Chung
Chul-Gyu Yoo
Young Whan Kim
Sung Koo Han
Young Sik Park

January 2016

BACKGROUND:The prognostic role of epidermal growth factor receptor (EGFR) mutations in patients with...

Epidermal growth factor receptor (EGFR) high gene copy number and activating mutations in lung adenocarcinomas are not consistently accompanied by positivity for EGFR protein by standard immunohistochemistry

F. PINTER
J. PAPAY
A. ALMASI
Z. SAPI
E. SZABO
M. KANYA
A. TAMASI
B. JORI
E. VARKONDI
J. MOLDVAY
K. SZONDY
G. KERI
S. ECKHARDT
L. KOPPER
R. SCHWAB
I. PETAK
DOMINICI, Massimo
CONTE, Pierfranco

January 2008

The purpose of this study was to investigate whether detectable protein biomarker overexpression is ...

Clinical Characteristics, Tumor, Node, Metastasis Status, and Mutation Rate in Domain of Epidermal Growth Factor Receptor Gene in Serbian Patients with Lung Adenocarcinoma

Zaric, Bojan
Stojsic, Vladimir
Kovacevic, Tomi
Sarcev, Tatjana
Tepavac, Aleksandar
Jankovic, Radmila
Spasic, Jelena
Radosavljevic, Davorin
Zarogoulidis, Paul
Vukobradovic-Djoric, Nevena
Perin, Branislav

September 2014

ObjectiveMutation rate in domain of EGFR gene varies between populations of lung cancer patients. Pr...

EGFR exon 19 in-frame deletion and polymorphisms of DNA repair genes in never-smoking female lung adenocarcinoma patients

Yang, SY

[[sponsorship]]基因體研究中心[[note]]已出版;[SCI];有審查制度;不具代表性[[note]]http://gateway.isiknowledge.com/gateway/G...

Activating mutations within the EGFR kinase domain: a molecular predictor of disease-free survival in resected pulmonary adenocarcinoma.

김세규
김주항
김호근
문진욱
박무석
박인규
장준
정경영
조병철
최혜진

January 2009

PURPOSE: Although epidermal growth factor receptor (EGFR) tyrosine kinase (TK) mutations are highly ...

EGFR Gene Copy Number Gain is Related to High Tumor SUV and Frequent Relapse after Adjuvant Chemotherapy in Resected Lung Adenocarcinoma

Koh, Youngil
Jang, Bogun
Jeon, Yoon Kyung
Kim, Tae Min
Lee, Se-Hoon
Kim, Dong-Wan
Chung, Doo Hyun
Kim, Young Tae
Kim, Young Whan
Heo, Dae Seog

April 2011

Objective: The purpose of our study was to define the prognostic impact of increased copies of epide...

Genetic and epigenetic analysis of erbB signaling pathway genes in lung cancer

HOQUE MO
BRAIT M
ROSENBAUM E
PAL P
BEGUM S
DASGUPTA S
CARVALHO AL
AHRENDT SA
WESTRA WH
SIDRANSKY D.
POETA, Maria Luana

January 2010

Prognosis for patients with non-small cell lung cancer (NSCLC) is poor. The potential value of modu...

Relationship between EGFR expression, copy number and mutation in lung adenocarcinomas

Wu Shafei
Gao Jie
Zeng Xuan
Zhang Jing
Liang Zhiyong
Liu Tonghua

July 2010

Abstract Background This study was designed to investigate EGFR protein expression, EGFR copy number...

Clustered Genomic Alterations in Chromosome 7p Dictate Outcomes and Targeted Treatment Responses of Lung Adenocarcinoma with Egfr-Activating Mutations

袁新盛
Yuan, Shinsheng

July 2012

Purpose Although epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have been...

Targeted Next-Generation Sequencing Analysis Predicts the Recurrence in Resected Lung Adenocarcinoma Harboring <i>EGFR</i> Mutations

In Ae Kim
Jae Young Hur
Hee Joung Kim
Song Am Lee
Jae Joon Hwang
Wan Seop Kim
Kye Young Lee

July 2021

Targeted NGS, widely applied to identify driver oncogenes in advanced lung adenocarcinoma, may also ...

Prognostic and Predictive Value of Epidermal Growth Factor Receptor Tyrosine Kinase Domain Mutation Status and Gene Copy Number for Adjuvant Chemotherapy in Non-small Cell Lung Cancer

Tsao, Ming-Sound
Sakurada, Akira
Ding, Keyue
Aviel-Ronen, Sarit
Ludkovski, Olga
Liu, Ni
Maître, Aurélie Le
Gandara, David
Johnson, David H.
Rigas, James R.
Seymour, Lesley
Shepherd, Frances A.

January 2011

Purpose:Patients with non-small cell lung carcinoma with epidermal growth factor receptor (EGFR) mut...

Epidermal growth factor receptor mutation status in stage I lung adenocarcinoma with different image patterns

Hsu, KH

[[sponsorship]]基因體研究中心[[note]]已出版;[SCI];有審查制度;不具代表性[[note]]http://gateway.isiknowledge.com/gateway/G...

Comprehensive Analysis of Epidermal Growth Factor Receptor Gene Status in Lung Adenocarcinoma

Li, Chenguang
Sun, Yihua
Fang, Zhaoyuan
Han, Xiangkun
Fang, Rong
Zhang, Yang
Pan, Yunjian
Zhang, Wenjing
Ren, Yan
Ji, Hongbin
Chen, Haiquan

June 2011

Introduction:The epidermal growth factor receptor (EGFR) gene status including tyrosine kinase domai...

Increased epidermal growth factor receptor (EGFR) gene copy number is strongly associated with EGFR mutations and adenocarcinoma in non-small cell lung cancers: A chromogenic in situ hybridization study of 182 patients

Chang, JWC

[[abstract]]To evaluate the association of epidermal growth factor receptor (EGFR) gene copy number ...

Prognostic implication of EGFR gene mutations and histological classification in patients with resected stage I lung adenocarcinoma.

Chun-Yu Lin
Yen-Mu Wu
Meng-Heng Hsieh
Chih-Wei Wang
Ching-Yang Wu
Ying-Jen Chen
Yueh-Fu Fang

January 2017

The prognostic value of epidermal growth factor receptor (EGFR) mutations and the correlation betwee...

The Association of EGFR Mutations with Stage at Diagnosis in Lung Adenocarcinomas.

Jaeyoung Cho
Sun Mi Choi
Jinwoo Lee
Chang-Hoon Lee
Sang-Min Lee
Jae-Joon Yim
Doo Hyun Chung
Chul-Gyu Yoo
Young Whan Kim
Sung Koo Han
Young Sik Park

January 2016

BACKGROUND:The prognostic role of epidermal growth factor receptor (EGFR) mutations in patients with...

Epidermal growth factor receptor (EGFR) high gene copy number and activating mutations in lung adenocarcinomas are not consistently accompanied by positivity for EGFR protein by standard immunohistochemistry

F. PINTER
J. PAPAY
A. ALMASI
Z. SAPI
E. SZABO
M. KANYA
A. TAMASI
B. JORI
E. VARKONDI
J. MOLDVAY
K. SZONDY
G. KERI
S. ECKHARDT
L. KOPPER
R. SCHWAB
I. PETAK
DOMINICI, Massimo
CONTE, Pierfranco

January 2008

The purpose of this study was to investigate whether detectable protein biomarker overexpression is ...

Clinical Characteristics, Tumor, Node, Metastasis Status, and Mutation Rate in Domain of Epidermal Growth Factor Receptor Gene in Serbian Patients with Lung Adenocarcinoma

Zaric, Bojan
Stojsic, Vladimir
Kovacevic, Tomi
Sarcev, Tatjana
Tepavac, Aleksandar
Jankovic, Radmila
Spasic, Jelena
Radosavljevic, Davorin
Zarogoulidis, Paul
Vukobradovic-Djoric, Nevena
Perin, Branislav

September 2014

ObjectiveMutation rate in domain of EGFR gene varies between populations of lung cancer patients. Pr...

EGFR exon 19 in-frame deletion and polymorphisms of DNA repair genes in never-smoking female lung adenocarcinoma patients

Yang, SY

[[sponsorship]]基因體研究中心[[note]]已出版;[SCI];有審查制度;不具代表性[[note]]http://gateway.isiknowledge.com/gateway/G...

Activating mutations within the EGFR kinase domain: a molecular predictor of disease-free survival in resected pulmonary adenocarcinoma.

김세규
김주항
김호근
문진욱
박무석
박인규
장준
정경영
조병철
최혜진

January 2009

PURPOSE: Although epidermal growth factor receptor (EGFR) tyrosine kinase (TK) mutations are highly ...

EGFR-activating mutations, DNA copy number abundance of ErbB family, and prognosis in lung adenocarcinoma

Abstract

Extracted data

EGFR-activating mutations, DNA copy number abundance of ErbB family, and prognosis in lung adenocarcinoma

Abstract

Extracted data

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