Recurrence rate after loop electrosurgical excision procedure (LEEP) and laser Conization: A 5-year follow-up study
- BOGANI G.
- DI DONATO V.
- SOPRACORDEVOLE F.
- CIAVATTINI A.
- GHELARDI A.
- LOPEZ S.
- SIMONCINI T.
- PLOTTI F.
- CASARIN J.
- SERATI M.
- PINELLI C.
- VALENTI G.
- BERGAMINI A.
- GARDELLA B.
- DELL'ACQUA A.
- MONTI E.
- VERCELLINI P.
- FISCHETTI M.
- D'IPPOLITO G.
- AGUZZOLI L.
- MANDATO V. D.
- CARUNCHIO P.
- CARLINFANTE G.
- GIANNELLA L.
- SCAFFA C.
- FALCONE F.
- BORGHI C.
- DITTO A.
- MALZONI M.
- GIANNINI A.
- SALERNO M. G.
- LIBERALE V.
- CONTINO B.
- DONFRANCESCO C.
- DESIATO M.
- PERRONE A. M.
- DONDI G.
- De IACO P.
- LEONE ROBERTI MAGGIORE U.
- SIGNORELLI M.
- CHIAPPA V.
- FERRERO S.
- SARPIETRO G.
- MATARAZZO M. G.
- CIANCI A.
- BOSIO S.
- RUISI S.
- GUERRISI R.
- BRUSADELLI C.
- MOSCA L.
- TINELLI R.
- DE VINCENZO R.
- ZANNONI G. F.
- FERRANDINA G.
- PETRILLO M.
- DESSOLE S.
- ANGIOLI R.
- GREGGI S.
- SPINILLO A.
- GHEZZI F.
- COLACURCI N.
- MUZII L.
- BENEDETTI PANICI P.
- SCAMBIA G.
- RASPAGLIESI F.
DOIAbstract
Objective: Conization aims to remove pre-neoplastic lesions of the uterine cervix. Several techniques for conization have been compared, but evidence regarding the most effective therapeutic option is scant. Here, we aimed to compare the recurrence rate following laser conization and loop electrosurgical excision procedure (LEEP) in patients with high-grade cervical dysplasia (HSIL/CIN2+). Methods: This is a retrospective multi-institutional study. Medical records of consecutive patients with HSIL/CIN2+ undergoing conization between 2010 and 2014 were retrieved. A propensity-score matching (PSM) was applied in order to reduce allocation bias. The risk of developing recurrence was estimated using Kaplan-Meir and Cox hazard models. Results: O...
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