Mapping and scheduling an application onto the processors of a parallel system is a difficult problem. This is true when performance is the only objective, but becomes worse when a second optimization criterion like reliability is involved. In this paper we investigate the problem of mapping an application consisting of several consecutive stages, i.e., a pipeline, onto heterogeneous processors, while considering both the performance, measured as throughput, and the reliability. The mechanism of replication, which refers to the mapping of an application stage onto more than one processor, can be used to increase throughput but also to increase reliability. Finding the right replication trade-off plays a pivotal role for this bi-criteria opt...