Recently new opportunities are emerging for improving the way patients with Haemophilia A are treated. Among these opportunities, efmoroctocog alfa is a first-in-class recombinant factor VIII-Fc fusion protein (rFVIIIFc) produced by recombinant DNA technology with an extended half-life compared with conventional FVIII preparations. The available evidence coming from an Italian HTA report indicates that efmoroctocog alfa provides an effective alternative to conventional FVIII preparations (including standard rFVIIIs) for the management of Haemophilia A. Moreover, by reducing the frequency of injections required, it has the potential to reduce treatment burden, and hence improve adherence to prophylaxis and patient Quality-of-Life. 
The concept of replacement therapy in haemophilia is changing significantly thanks to the switch fro...
Hemophilia unfortunately a less attracted disease for researchers compared to other life threatening...
Recombinant DNA technology has led to accelerating introduction of novel therapeutics for the treatm...
Recently new opportunities are emerging for improving the way patients with Haemophilia A are treate...
Recently new opportunities are emerging for improving the way patients with Haemophilia A are treate...
Haemophilia therapy has undergone very rapid evolution in the last 10 years. The major limitation of...
Emanuela Marchesini,1 Massimo Morfini,2 Leonard Valentino3,4 1Hemophilia Centre, SC Vascular and Eme...
International audienceBackground Efmoroctocog alfa, the first recombinant factor VIII fusion protein...
International audienceBackground Efmoroctocog alfa, the first recombinant factor VIII fusion protein...
International audienceBackground Efmoroctocog alfa, the first recombinant factor VIII fusion protein...
Introduction: Haemophilia A is a rare bleeding disorder caused by coagulation factor VIII (FVIII) de...
The current interest in recombinant factor VIII (rFVIII) products stems from the fact that they offe...
BAY 81-8973 is an unmodified, full-length third generation recombinant factor VIII (rFVIII) which of...
The current interest in recombinant factor VIII (rFVIII) products stems from the fact that they offe...
BAY 81-8973 is an unmodified, full-length third generation recombinant factor VIII (rFVIII) which of...
The concept of replacement therapy in haemophilia is changing significantly thanks to the switch fro...
Hemophilia unfortunately a less attracted disease for researchers compared to other life threatening...
Recombinant DNA technology has led to accelerating introduction of novel therapeutics for the treatm...
Recently new opportunities are emerging for improving the way patients with Haemophilia A are treate...
Recently new opportunities are emerging for improving the way patients with Haemophilia A are treate...
Haemophilia therapy has undergone very rapid evolution in the last 10 years. The major limitation of...
Emanuela Marchesini,1 Massimo Morfini,2 Leonard Valentino3,4 1Hemophilia Centre, SC Vascular and Eme...
International audienceBackground Efmoroctocog alfa, the first recombinant factor VIII fusion protein...
International audienceBackground Efmoroctocog alfa, the first recombinant factor VIII fusion protein...
International audienceBackground Efmoroctocog alfa, the first recombinant factor VIII fusion protein...
Introduction: Haemophilia A is a rare bleeding disorder caused by coagulation factor VIII (FVIII) de...
The current interest in recombinant factor VIII (rFVIII) products stems from the fact that they offe...
BAY 81-8973 is an unmodified, full-length third generation recombinant factor VIII (rFVIII) which of...
The current interest in recombinant factor VIII (rFVIII) products stems from the fact that they offe...
BAY 81-8973 is an unmodified, full-length third generation recombinant factor VIII (rFVIII) which of...
The concept of replacement therapy in haemophilia is changing significantly thanks to the switch fro...
Hemophilia unfortunately a less attracted disease for researchers compared to other life threatening...
Recombinant DNA technology has led to accelerating introduction of novel therapeutics for the treatm...