Synthesis and Characterization of Chitosan-Citrate Microparticle Using Ionic Gelation Methods

A study has been conducted aimed to synthesize chitosan-citrate using the ionic gelation method and its characterization with FTIR, SEM, SAA, and PSA, as well as solubility and swelling tests. The results showed that chitosan reacted with sodium citrate producing chitosan-citrate particles. The product of chitosan-citrate has a rough and thickened surface morphology. Surface area is obtained by 35.233 m2/g and pore size is 0.027 cc/g, smaller than chitosan. Based on solubility and swelling tests in acidic, alkaline, and neutral media, chitosan-citrate has good resistance and low swelling effect