Recommendation prophilaxis in all congenital factor XIII deficiency with abnormal ureaclot lysis test
- Mirbehbahani, N.
DOIAbstract
Introduction: Routine prophilaxis with FXIII concentrate is recommended in all individuals with FXIII levels of <1 IU dL⁻¹ from the time of diagnosis and in some severely affected patients with FXIII levels of 1–4 IU dL⁻¹. In Iran, ureaclot lysis test (FXIII screen) is the most available test and reliable assays are not accessible because of limitations of laboratory equipment and the aim of this study was to determine cases that need to prophilaxy with attention to limitations of laboratory equipment in Iran. Methods: There were 110 patients with hemophilia and rare bleeding disorders in Golestan pronice, Iran, involving 65 hemophila A, 13 hemophilia B and 32 rare bleeding disorders that 6 cases had FXIII deficiency. 5 patients with FXIII ...