Acid Promoted One-Pot Processes: Efficient Synthesis of Indanones, Indenones, Spiro Tetracyclic Indanones, Indenes and Indanes

One-pot synthetic processes are considered as convenient methods to synthesize organic molecules with high degree of complexity, without isolating intermediates. These processes proved to have several advantages over step-wise operations, as it avoids the isolation of intermediate species, thereby considerably reducing the waste generation, increasing efficiency, minimizing the use of solvents, reagents, time and energy. Moreover, it was also found that in most cases the overall yields in one-pot processes are usually higher than those obtained from the corresponding step-wise operations. Herein, we have developed efficient one-pot synthetic strategies for the synthesis of 1-indanones, indenones, novel spiro-tetracyclic indanones, indenes and indanes