International audienceBackground: Cisplatin-based combination chemotherapy before surgery is the standard of care for muscle-invasive bladder cancer. However, the optimal chemotherapy modalities have not been precisely defined to date.Patients and methods: In the VESPER trial, patients received after randomization either gemcitabine and cisplatin (GC, 4 cycles) or methotrexate, vinblastine, doxorubicin and cisplatin (dose dense [dd]-MVAC, 6 cycles). Creatinine clearance (CrCl) was calculated before each cycle according to the Cockroft and Gault formula. Definition criteria for local control after neoadjuvant chemotherapy included pathological complete response (ypT0N0), pathological downstaging (<ypT2N0) and organ-confined disease (<ypT3N0)...
International audienceNeoadjuvant cisplatin-based chemotherapy (NAC) followed by radical cystectomy ...
The aim of this study was to investigate the outcome of patients with muscle-invasive bladder cancer...
Introduction: Neoadjuvant cisplatin-based combination chemotherapy improves survival in muscle-invas...
International audienceBackground: Cisplatin-based combination chemotherapy before surgery is the sta...
International audienceBackground: Cisplatin-based combination chemotherapy before surgery is the sta...
International audienceBackground: Cisplatin-based combination chemotherapy before surgery is the sta...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceNeoadjuvant cisplatin-based chemotherapy (NAC) followed by radical cystectomy ...
The aim of this study was to investigate the outcome of patients with muscle-invasive bladder cancer...
Introduction: Neoadjuvant cisplatin-based combination chemotherapy improves survival in muscle-invas...
International audienceBackground: Cisplatin-based combination chemotherapy before surgery is the sta...
International audienceBackground: Cisplatin-based combination chemotherapy before surgery is the sta...
International audienceBackground: Cisplatin-based combination chemotherapy before surgery is the sta...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceThe main objective of the French GETUG/AFU V05 VESPER randomized phase III stu...
International audienceNeoadjuvant cisplatin-based chemotherapy (NAC) followed by radical cystectomy ...
The aim of this study was to investigate the outcome of patients with muscle-invasive bladder cancer...
Introduction: Neoadjuvant cisplatin-based combination chemotherapy improves survival in muscle-invas...