Clindamycin-induced necrotising oesophagitis

A 43-year-old Caucasian female patient was admitted to the emergency department with chest pain and dysphagia for solids and liquids. Symptoms began after she took clindamycin 300 mg orally for one day and had been worsening for 24 h before she came to hospital. A constant, squeezing pain had started behind her breastbone, spreading to the upper stomach and back and was worsened by swallowing and movement. No nausea, vomiting, dyspnoea or fever was observed. Clindamycin had been prescribed as an antimicrobial prophylaxis before oral surgery (apicoectomy)